Rachelle Landgraf is an analytical chemistry professional with over 10 years of experience and expertise in analytical method development and mass spectrometry. She is a classically trained mass spectometrist with the ability to analyze a broad range of compounds from small molecules to proteins utilizing an array of sample preparation techniques with mass spectrometric detection. She has collaborated with nationally recognized companies as well as top tier research organizations.

Mass Spectrometry

MALDI-TOF

LC-MS

Professional Background

Marine Ventures International, Inc., Consultant | 5 months

Wildcat Pharmaceutical Development Center, Mass Spectrometry Director, Senior Scientist | 3 years, 6 months

The University of Texas MD Anderson Cancer Center, Research Scientist | 2 years, 5 months

The Scripps Research Institute-Florida, Research Associate | 2 years, 2 months

The University of Florida, Research Assistant | 4 years, 5 months

Education

Ph.D., Analytical Chemistry, The University of Florida, 2009
B.S., Chemistry, Texas A&M University-Corpus Christi, 2004

Activation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange mass spectrometry” Rachelle R. Landgraf, Devrishi Goswami, Francis Rajamohan, Melissa S. Harris, Matthew F. Calabrese, Lise R. Hoth, Rachelle Magyar, Bruce D. Pascal, Michael J. Chalmers, Scott A. Busby, Ravi G. Kurumbail, Patrick R. Griffin. Structure. 2013. 21, 1942-1953.

“HDX Workbench: Software for the Analysis of H/D Exchange MS Data” Bruce D. Pascal, Scooter Willis, Jeni L. Lauer, Rachelle R. Landgraf, Graham M. West, David Marciano, Scott Novick, Devrishi Goswami, Michael J. Chalmers, Patrick R. Griffin. Journal of the American Society for Mass Spectrometry. 2012. 23, 1512-1521.

“Automated Hydrogen/Deuterium Exchange Electron Transfer Dissociation High Resolution Mass Spectrometry Measured at Single-Amide Resolution” Rachelle R. Landgraf, Michael J. Chalmers, Patrick R. Griffin. Journal of the American Society for Mass Spectrometry. 2011. 23, 301-309.

“Considerations for quantification of lipids in nerve tissue using matrix-assisted laser desorption/ionization mass spectrometric imaging” Rachelle R. Landgraf, Timothy J. Garrett, Maria C. Prieto Conaway, Nigel A. Calcutt, Peter W. Stacpoole, Richard A. Yost. Rapid Communications in Mass Spectrometry. 2011. 25, 3178-3184.

“Imaging of Lipids in Spinal Cord Using Intermediate Pressure Matrix-Assisted Laser Desorption-Linear Ion Trap/Orbitrap MS” Rachelle R. Landgraf, Timothy J. Garrett, Maria C. Prieto Conaway, Peter W. Stacpoole, Richard A. Yost. Analytical Chemistry. 2009. 81, 8488-8495.

"MALDI-Linear Ion Trap Microprobe MS/MS Studies of the Effects of Dichloroacetate on Lipid Content of Nerve Tissue" Rachelle R. Landgraf, Timothy J. Garrett, Nigel A. Calcutt, Peter W. Stacpoole, Richard A. Yost. Analytical Chemistry. 2007. 79, 8170 – 8175.